The many types of heart defects generally fall into 3 categories. In each group, a hole in the heart allows blood to flow incorrectly from one area to another. Your doctor may call this “shunting.” Different forms of CHD have different kinds of shunts.
The heart is a 2-sided pump. The right side of the heart collects oxygen-poor blood from the rest of the body. It pumps that blood to the lungs to pick up oxygen. The oxygen-rich blood returns to the left side of the heart from the lungs. The heart pumps it back throughout the body.
A left-to-right shunt is a heart defect that allows oxygen-rich blood to move from the left side of the heart to the right side.
A right-to-left shunt is a defect that allows oxygen-poor blood to move from the right side of the heart to the left side and into the circulation.
A mixing lesion is a defect that has both left-to-right and right-to-left shunting.
Children should not receive SYNAGIS if they have ever had a severe allergic reaction to it. Signs and symptoms of a severe allergic reaction could include itchy rash; swelling of the face; difficulty swallowing; difficulty breathing; bluish color of the skin; muscle weakness or floppiness; and/or unresponsiveness. If your child has any of these signs or symptoms of a severe allergic reaction after getting SYNAGIS, call your child’s healthcare provider or get medical help right away.
SYNAGIS is given as a monthly injection, usually in the thigh (leg) muscle, by your child’s healthcare provider. If your child has a problem with bleeding or bruises easily, an injection could cause a problem. Your child should receive their first injection of SYNAGIS before the RSV season starts, to help protect them before RSV becomes active. RSV season is usually fall through spring, but it may begin earlier or last longer in certain areas. When RSV is most active, your child will need to receive injections of SYNAGIS every 28-30 days to help protect them from severe RSV disease for about a month. Your child should continue to receive monthly injections of SYNAGIS until the end of RSV season. Your child may still get severe RSV disease after receiving SYNAGIS. If your child has an RSV infection, they should continue to get their monthly injections throughout the RSV season to help prevent severe disease from new RSV infections.
The effectiveness of injections of SYNAGIS given less than monthly throughout the RSV season has not been established.
Serious side effects include severe allergic reactions, which may happen after any injection of SYNAGIS and may be life-threatening or cause death. Call your child’s healthcare provider or get medical help right away if your child has any of the signs or symptoms of a serious allergic reaction. See “Who should not receive SYNAGIS?” for more information.
Common side effects of SYNAGIS include fever and rash.
These are not all the possible side effects of SYNAGIS.
SYNAGIS is a prescription medication that is used to help prevent a serious lung disease caused by respiratory syncytial virus (RSV) in children:
It is not known if SYNAGIS is safe and effective:
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